Navigating SIBO: Understanding, Testing, and Dietary Strategies

In the complex world of digestive health, Small Intestinal Bacterial Overgrowth (SIBO) emerges as a significant player, impacting more than just our gastrointestinal well-being. Did you know that up to 78% of irritable bowel syndrome (IBS) cases may be linked to SIBO? This striking statistic underscores the urgency of understanding and addressing this often-overlooked condition.

SIBO, marked by an abnormal increase in bacteria within the small intestine, disrupts the delicate balance of our digestive ecosystem. Beyond discomfort, it jeopardizes nutrient absorption, immune function, and overall well-being. This blog post acts as a guide through the complexities of SIBO, exploring its origins and far-reaching effects. We'll spotlight the crucial role of testing, providing insights into diagnostic approaches for targeted interventions.

But the journey doesn't stop at diagnosis; we'll also navigate the dietary strategies essential for managing SIBO. From personalized nutrition plans to lifestyle adjustments, we'll uncover the keys to creating an environment that discourages bacterial overgrowth and fosters a resilient digestive system.

Understanding SIBO

SIBO, or Small Intestinal Bacterial Overgrowth, occurs when bacteria, typically found in the colon, proliferate within the small intestine. In a healthy state, the small intestine allows the passage of bacteria, but built-in mechanisms prevent excessive colonization. When these safeguards falter, bacterial overgrowth takes place, leading to inflammation in the small intestine. This, in turn, triggers complications such as leaky gut, maldigestion, and even autoimmune flares.

Due to increased inflammation in the gut lining and an imbalance in the bacterial microbiome, malapsorption of fats, carbs, and proteins can occur, as well as vitamins and minerals that are needed to heal and fuel the body.

Distinct subtypes of SIBO have been identified based on breath test results and the predominant gas types produced by microorganisms in the gastrointestinal tract. Hydrogen-SIBO involves the overgrowth of bacteria that produce hydrogen within the small intestine. Hydrogen sulfide-SIBO, on the other hand, is characterized by the overgrowth of bacteria producing hydrogen sulfide in the small intestine. Another variant is Intestinal Methanogen Overgrowth (IMO), marked by the overgrowth of archaea (organisms resembling bacteria) in either the small or large intestines.

Common SIBO Symptoms

  • Loss of appetite

  • Abdominal pain

  • Nausea

  • Heartburn

  • An uncomfortable bloating or fullness after eating

  • Diarrhea

  • Unintentional weight loss

  • Malnutrition or malabsorption

What Causes SIBO

SIBO arises when the innate protective defenses against bacterial overgrowth within the small intestine are compromised, dysfunction occurs, and abnormalities in motility, immune function, digestive enzymes, and anatomy. These factors collectively contribute to the development of SIBO, unraveling the intricate web of causative elements behind this gastrointestinal condition.

Common Increased Risk Factors:

  • Low stomach acid

  • Acid reducing Medications (PPIs, Tums, Pepcid, Prilosec, immunosuppressants)

  • Gastroparesis

  • Celiac Disease

  • Chronic Constipation

  • Slow digestion/motility

  • Surgery (scar tissue: C section, endometriosis, hysterectomy, tummy tuck)

  • Hypothyroid or Hashimoto’s

  • Stress, High Cortisol, or Adrenal Dysfunction

  • A diet high in sugar, processed carbs, and alcohol

  • Infection

  • Food poisoning

  • Structural (ileocecal valve disorder, bariatric)

How is SIBO Different from IBS

Irritable Bowel Syndrome (IBS) is classified as a functional gastrointestinal (GI) condition, rooted in disruptions to the brain-gut axis. Although the exact cause remains unknown, several factors have been associated with IBS, including early-life stressful events, bacterial infections, Small Intestinal Bacterial Overgrowth (SIBO), food intolerances, sensitivities, anxiety, and depression.

  • IBS presents with varying symptom profiles, leading to further categorization:

    IBS with predominant constipation (IBS-C)

    IBS with predominant diarrhea (IBS-D)

    IBS with mixed bowel habits (IBS-M)

SIBO, on the other hand, manifests as an overgrowth of bacteria and microorganisms in the small intestines, often causing symptoms akin to IBS, such as abdominal pain and diarrhea. The precise cause of SIBO is not fully understood. Normally, the upper small intestines maintain a low microbial count due to stomach acid and regular muscular contractions.

Conditions associated with reduced stomach acid production or disturbances in small intestine motility, including connective tissue disorders, chronic opioid use, diverticulitis, small bowel adhesions, and diabetic enteropathy, have been linked to SIBO.

Interestingly enough, both are often aggravated by emotional stress, overwhelm, and upset. Here is an article that looks at the connection between stress and gut health.

Testing for SIBO

The primary diagnostic tool for Small Intestinal Bacterial Overgrowth (SIBO) is the SIBO breath test, a widely used and non-invasive at-home test designed to assess bacterial overgrowth in the small intestine.

The process begins with patients fasting overnight to establish a baseline reading. The next morning, they ingest a specialized mixture to provoke the release of gases, specifically hydrogen, methane, or a combination of both, by bacteria in the small intestine. Following the ingestion, patients are instructed to provide breath samples over a 3-hour timeframe at specific intervals: 20 minutes, 40 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, and 180 minutes. This comprehensive sampling allows for the observation of gas levels, aiding in the identification of potential bacterial overgrowth and contributing to a more accurate diagnosis of SIBO.

Other Labs Utilized in the Assessment of SIBO and Related Conditions

In the realm of functional medicine, tailored diagnostic tools play a pivotal role in crafting individualized treatment plans for patients dealing with Small Intestinal Bacterial Overgrowth (SIBO) and its associated medical conditions. Here are some common labs ordered for this purpose:

  • Comprehensive Stool Analysis:

    A comprehensive stool analysis aids in identifying dysbiotic patterns contributing to SIBO-related diseases. It also assesses malabsorption, intestinal inflammation, and immune function by measuring fecal fats, bile acids, calprotectin, and secretory IgA (sIgA). The GI-MAP, a frequently ordered test, is particularly useful for ruling out H. pylori infection, a potential factor in rosacea.

  • Nutritional Evaluation:

    Examining nutrient imbalances associated with SIBO can be achieved through a comprehensive nutritional assessment. Elevated folate and deficiencies in iron, vitamin D, and B12 are common findings in SIBO. Deficiencies in iron and vitamin D are also linked to Restless Leg Syndrome (RLS).

    These labs offer valuable insights into dysbiotic patterns, nutritional imbalances, and factors contributing to SIBO and associated conditions.

A Functional Approach To Treating SIBO

The clinical management of Small Intestinal Bacterial Overgrowth (SIBO) encompasses a multifaceted approach, involving nutritional therapy, antimicrobial intervention, motility supplements, and preventative measures to deter reoccurrence. Specific measures will different based on symptoms, test results, age, medications, and other factors.

Nutritional Therapy: Low FODMAP and Elemental Diet

In the realm of nutritional therapy, practitioners often advocate for either a Low FODMAP or Elemental Diet to mitigate bacterial overgrowth. The Low FODMAP diet, designed to decrease the proliferation of bacteria, involves a three-step process. Initially, high FODMAP foods are eliminated, followed by a gradual reintroduction after 4 to 6 weeks to identify problematic foods causing discomfort. Once identified, these foods can be limited or avoided, allowing a return to a more balanced diet.

On the other hand, the Elemental Diet, a preference among functional medicine practitioners, is an intensive two-week regimen. Patients substitute all meals with an elemental nutrient drink, effectively starving the overgrown bacteria. Notably strict, this diet boasts a high success rate and obviates the need for herbal antimicrobial treatment during its implementation.

Herbal Antimicrobials

Functional Medicine Practitioners commonly integrate herbal antimicrobials, such as allicin and berberine, into a low FODMAP diet regimen lasting 4-6 weeks. Patients should be forewarned about potential bacterial and candida die-off reactions, which may induce temporary discomfort before improvement within 3-4 weeks of treatment.

Herbal Antimicrobials Based on SIBO Dominance

The choice between allicin and berberine hinges on the dominant SIBO type:

  • Methane Dominant SIBO: Allicin

  • Hydrogen Dominant SIBO: Berberine

  • Methane & Hydrogen Dominant SIBO: Combination of Allicin + Berberine

SIBO disrupts the delicate balance of the digestive ecosystem, leading to inflammation, complications such as leaky gut and bloating, chronic constipation, slow digestion, and even autoimmune flares. Please explore some of the testing options that have been linked and listed above, as well as supports like allicin and berberine.

In the intricacies of digestive health, Small Intestinal Bacterial Overgrowth (SIBO) emerges as a significant contributor, impacting not only gastrointestinal well-being but also interconnected aspects of our overall health. Hence, why it is important to get help from a functional practitioner and seek intervention when signs arise.

If you’re looking for a simple DIY way to reduce inflammation in your gut, and improve gut issues like bloating, constipation, or diarrhea, check out our Gut Health Reset course HERE.

To explore a functional approach to supporting SIBO, including lifestyle interventions, antimicrobials, and tailored supplement plans, click the button below to work with me.

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